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Mapi Pharma has filed an adapted F-1 anatomy with the U.S. Securities and Exchange Commission (SEC) apropos its antecedent accessible alms (IPO). No appraisement capacity were accustomed in the filing, nor was there a appraisal associated with the offering. The aggregation intends to account on the Nasdaq Global Market beneath the attribute MAPI.

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The underwriters for the alms are JMP Securities, FBR and Maxim Group.

This ytic date biologic aggregation is affianced in the development of bigger extended-release versions of absolute commercially acknowledged products, which it refers to as activity aeon administration (LCM) products, that ambition ample markets, as able-bodied as high-barrier to access and high-added amount all-encompassing drugs.

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The LCM articles are new forms of marketed drugs that Mapi believes may action advantages over absolute formulations, such as bigger accommodating acquiescence and bargain ancillary effects, and acquiesce continued apparent and authoritative exclusivity due to altered formulations of artefact components, for archetype through annex or extended-release formulations. Its annex drugs are non-oral formulations absolute assorted doses of a biologic and are advised to absolution the biologic over specified, generally prolonged, periods. These LCM artefact candidates seek to add amount to drugs that are accepted to go off-patent by amalgam off-patent alive biologic capacity with its formulations, consistent in a new final aggregate that they accept to be patentable.

Mapi’s advance artefact applicant is Glatiramer Acetate Depot, a once-monthly bang for the ysis of patients with relapsing-remitting assorted sclerosis, in adverse to the circadian 20 mg and the thrice-weekly 40 mg dosage of Copaxone, Teva’s accustomed artefact for the aforementioned indication. Branded Copaxone had sales of $4.2 billion in 2014.

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The aggregation is developing two added LCM articles targeting ample markets. Mapi is developing Pregabalin ER, an continued absolution articulate anatomy of Lyrica, Pfizer’s Pregabalin-based drug, for the ysis of neuropathic affliction and attack which had sales of $5.2 billion in 2014. Also the aggregation is developing Risperidone LAI , a once-monthly annex conception of Johnson & Johnson’s Risperdal Consta for the ysis of schizophrenia and bipolar disorder, which had sales of $1.2 billion in 2014.

The net gain from the alms are advised to be acclimated to aggrandize the ytic development program, with the put against alive basic and accepted accumulated purposes.

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