UNITED STATES – Older women who consistently took aspirin, but not agnate anti-inflammatory drugs, had a lower-than-average accident of developing melanoma, the best alarming anatomy of bark cancer, according to a US study.
Melanoma cases accept been on the acceleration in contempo decades. The American Blight Society estimates that about 77,000 new melanomas will be diagnosed in 2013 and aloof over 9,000 bodies will die of the disease.
The findings, appear in the anniversary Cancer, are based on 12 years of abstracts from the large, abiding Women’s Health Initiative abstraction and anniversary for how abundant time abstraction participants spent in the sun and whether they about acclimated sunscreen.
But advance columnist Jean Tang, from the Stanford University School of Medicine in California, said that this does not beggarly all women should alpha demography aspirin to area off bark cancer.
“This abstraction … correlates use of aspirin with lower melanoma accident but doesn’t prove it,” Tang told Reuters Health.
For their study, Tang and her colleagues tracked about 60,000 white women, ages 50 to 79, who appear their medication use and any new diagnoses on anniversary questionnaires.
During the ysis period, 548 women – beneath than one per cent – were diagnosed with melanoma.
Women who said they were consistently demography aspirin, acceptation at atomic alert a week, at the alpha of the abstraction were 21 per cent beneath acceptable to advance melanoma than those not on anti-inflammatory medicines. Use of aspirin for bristles years or best was angry to a 30 per cent abridgement in bark blight risk.
However, women who took added non-steroidal anti-inflammatories (NSAIDS) – such as ibuprofen and naproxen – weren’t any beneath acceptable to advance melanoma. Neither were users of acetaminophen.
Aspirin and added NSAIDS arrest assertive proteins that are accepted to comedy a role in tumour growth, so it’s not bright why aspirin abandoned ability lower the accident of melanoma.
According to Tang, it’s accessible there aloof weren’t abundant women demography non-aspirin NSAIDS in the abstraction to see a bright effect.
But Randall Harris, a blight researcher from The Ohio State University Medical Center in Columbus, Ohio, said the affirmation has been axle up that aspirin and added NSAIDS are angry to a lower accident of a ambit of cancers, including , colon and lung cancer.
“In my opinion, it’s absolutely account because demography one of these compounds on a approved base at a almost low dosage … two or three times per week, abnormally if you are at accident for developing any one of these malignancies,” he said.
But Tang doesn’t anticipate the affirmation currently supports best bodies application these drugs to area off cancer, including melanoma.
“For women who are at aerial accident (such as) somebody who’s already had bark cancer, allocution to your doctor about demography aspirin, because aspirin is still a drug,” she said. “The account needs to be advised adjoin some of the accessible ancillary effects.”
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